| 货号 | 纯度 | 规格 | 目录价 | 会员价 | 库存 | 数量 | 购买 |
|---|---|---|---|---|---|---|---|
| AK19798-100ul | 100ul | 100ul | ¥2680.00 | 登录查看 |
|
Cat. No. AK19798
Package 100 μl
StoragePBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Product overview
Description Anti-KEAP1 mouse monoclonal antibody
Applications WB, IHC, FC
Immunogen Fusion protein of human KEAP1
Reactivity Human, Mouse
Content 1 mg/ml
Host species Mouse
Ig class IgG1
Purification Purified from mouse ascites fluids by affinity chromatography
Target information
Symbol KEAP1
Full name kelch like ECH associated protein 1
Synonyms Nrf2; KLHL19
Swissprot Q14145
Target Background
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like
ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the
proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in
the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript
variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
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